| Name | Reviewer | Quote | Score |
| IGN.com (GameCube) | Fran Mirabella III | Metroid Prime has undergone the same Brilliant translation into 3D that Nintendo's acclaimed Legend of Zelda franchise has. | 9.8 out of 10 |
| GameSpot.com (GameCube) | Greg Kasavin | It's not just one of the single most atmospheric Games ever created, but it's also quite simply one of the best. | 9.7 out of 10 |
| GamePro.com (GameCube) | The D-Pad Destroyer | Still, even with its minor problems, Samus’s latest adventure is a perfect tribute to the Metroid we all know and love. | 4.5 out of 5 |
| GameSpy.com (GameCube) | Bryn Williams | Put simply, if you own a GameCube, you need to play this game. It doesn't get any better than this. | 96 out of 100 |
| GamesDomain.com (GameCube) | Brett Todd | It's certainly the most entertaining release that the Gamecube has seen thus far, and is a must for anyone who owns the system. | 4.5 out of 5 |
| Game-Revolution.com (GameCube) | Johnny Liu | Despite all the arguments that Metroid should have been in the third person, this is a fantastic, top-notch Effort and a simple must-have for anyone with a Gamecube. | A |
| The Electric Playground (GameCube) | Jules Grant | The marvelous gameplay will actually wow you at times, and Metroid Prime puts to bed any doubt that Nintendo publishes the absolute best playing games in the business. | 8.0 out of 10 |
| ArmchairEmpire.com (GameCube) | Omni | If you own a GameCube, you owe it to yourself to at the very least rent Metroid Prime if you don't buy it outright. | 10.0 out of 10 |
| AllRPG.com (GameCube) | Justin Holmes | Everything in this game is just implemented flawlessly. Taking things like the grapple beam and Spider Ball that one would never imagine could be brought to a 3D game and pulling them off with flying colours just Speaks momentarily on the experience this game is. | 9.0 out of 10 |
| Snackbar-Games.com (GameCube) | Pickle | Metroid will cater to the tastes of so Many gamers. | N/A |
| GamersHell.com (GameCube) | Bill K. | I am stunned. Smooth as silk, I am more and more impressed with what the Gamecube is capable of. | 9.0 out of 10 |
| TechTV.com (GameCube) | AM Urbanek | Retro Studios has brought 'Metroid' into 3D gaming with such perfection, that it's Hard to understand why there was ever any resistance to the concept... A Welcome addition to the series, it's difficult to Find any shortcomings in the title. | 5.0 out of 5 |